Climate change is accelerating the emergence and spread of “superbugs”, which are antibiotic resistant and thrive in warm, wet conditions. Higher temperatures have been found to promote the growth, infection and spread of antibiotic resistance in bacteria, both in humans and animals. Flooding from extreme weather events overloads sanitation infrastructure, increases congestion in already-crowded regions, and propagates antibiotic resistance through the flow and overflow of sewage – a proven reservoir for antibiotic resistance genes. An increase in rainfall will also result in increased runoff from farms and industry and, consequently, result in higher levels of pollutants in the water. Environmental pollutants have been shown to promote the production of antibiotic resistance genes and increase bacterial mutations that can exacerbate resistance. Increased nutrient-rich agricultural runoff will enhance the likelihood of algal blooms in water systems, and high bacterial concentrations will boost opportunities for the transfer of antibiotic resistance genes. Droughts present problems too, as water scarcity leads to reduced sanitation and results in higher densities of people sharing the same water source or using contaminated water for agricultural purposes. Crowding and sharing water can increase the likelihood of waterborne diseases becoming epidemics, as common symptoms such as diarrhoea and vomiting cause further reductions in hygiene and increase contamination of water. Malnutrition, overcrowding and inadequate sanitation all increase the risk of children contracting antibiotic-resistant gut infections. This will inevitably result in more severe diarrhoea; a point of concern if antibiotic resistance increases as it would prevent current medications from being effective. The shared environment for humans and animals is increasingly overlapping as the global population grows. This increases the likelihood of pathogen transmission and resistance between the environment, humans and animals. If climate change is not addressed, it will have a disproportionate impact on the health and wellbeing of people, especially in low- and middle-income countries around the world.